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Introduction

A Phylogenetic tree or Phylogram, sometimes called the 'Tree of Life', shows the evolutionary relationships among various people that are believed to have a common ancestor. Each node with descendants represents the most recent common ancestor of the descendants, with edge lengths in our tree, corresponding to time estimates. Each node in a phylogenetic tree is called a taxonomic unit.

Although phylogenetic trees can provide evolutionary insight, they do have important limitations. Phylogenetic trees do not necessarily (and likely do not) represent actual evolutionary history. The data on which they are based is noisy and recombination and back mutations can all confound the analysis.

Analysis of Irish Type III

Presently the Irish Type III cluster has 81 haplotypes that consist of, at least, FTDNA's 67 markers. These data were taken and analysed to produce this phylogram. Dean McGee’s Y-DNA Comparison Utility http://www.mymcgee.com/tools/yutility.html was used to produce a text file containing the relative-mutations matrix data needed by the SplitTrees4 program for inferring phylogenies (evolutionary trees).

An extremely fast and simple-to-use free program, SplitsTrees4 is being used to construct the Phylogenetic tree for the Irish Type III cluster. Splitstree4 can be downloaded from www.splitstree.org  
Citation:- D. H. Huson & D. Bryant Application of Phylogenetic Networks in Evolutionary Studies, Molecular Biology and Evolution, 23(2):254-267, 2006 and http://www.math.auckland.ac.nz/~bryant/Papers/04NeighborNet.pdf  

For this exercise I have used the network form of the phylogram. (Last update - 23 May 2008).

Cautionary Note:- The tree gives some indication of how closely each of the families are related to one another but this method of time estimation is considered to only be reasonable in the longer term and relatively inaccurate in the shorter term.

Click Here to download the Network as a pdf file.

  
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What's New

I have run a new calculation of the age of our cluster using a set of 181 37-marker haplotypes and a second set of 81 67-marker haplotypes.

These result is 993 years and 966 years respectively ... certainly about the time of Brian Boru!

A further run omitting the variable markers, 385, 389, 459, 464 and CDY resulted in a time of 1086 years with an error of ±20%.

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© Dennis Wright 08 November 2006 - Last updated - 27 June 2008

Legal Notice:

Dennis Wright, Coordinator of the Irish Type III DNA Website, does not assume any legal liability or responsibility for the accuracy, completeness, or usefulness of any information on these pages, nor does he represent that its use would not infringe on privately owned rights.  Further, Dennis Wright disclaims any and all warranties, express or implied, relating to this website and any information contained therein, including warranties as to the accuracy or completeness of the information.  Dennis Wright shall not be liable for any damages of any kind, under any theory of liability, resulting from user's access to the website or use of any information contained therein.

 
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